MgO纳米颗粒增强壳聚糖复合薄膜及其抗菌性能研究

Research on MgO Nanoparticle Reinforced Chitosan Composite Film and Its Antibacterial Property

中文关键词:  壳聚糖  MgO纳米颗粒  抗菌材料

Key Words:chitosan  MgO nanoparticles  antibacterial material

中文摘要:

      采用聚甲基丙烯酸甲酯（PMMA）/碳酸镁预聚物原位合成方法制备球形氧化镁（MgO）纳米颗粒，与壳聚糖复合制备壳聚糖/MgO复合薄膜，研究其力学性能、热稳定性、阻隔性能及抗菌性能。MgO纳米颗粒添加量为5 wt%时，壳聚糖/MgO复合薄膜获得最佳的力学性能，拉伸应力及弹性模量分别较壳聚糖薄膜提高64%及50%。傅里叶红外光谱（FT-IR）结果表明，壳聚糖/MgO复合薄膜力学性能的提升主要是由于壳聚糖的羟基和胺基与MgO形成了氢键。此外，添加5 wt% MgO纳米颗粒后，复合薄膜的氧气透过常数降低了约18%，该薄膜在12 h内可使46%的大肠杆菌结构破坏或死亡，具有优异的抗菌效果。

Abstract:

      This paper mainly introduced the mechanical， thermodynamic and antibacterial properties of spherical magnesium oxide （MgO） nanoparticle reinforced chitosan composite film prepared by in situ synthesis of polymethyl methacrylate （PMMA）/magnesium carbonate prepolymer. When the content of MgO nanoparticles was 5 wt%, the tensile stress and elastic modulus of chitosan/MgO composite film increased by 64% and 50%， respectively， reaching the optimal values. The FT-IR spectrum indicated that the improvement of mechanical properties was mainly due to the hydrogen bond interaction between the hydroxyl and amine groups on chitosan and MgO. In addition， after adding 5 wt% MgO nanoparticles， the oxygen permeability of chitosan composite film was reduced by ~18% and 46% of E. coli was destroyed or killed within 12 h， showing excellent antibacterial performance.